Generic Name:

Rasburicase

Storage Condition:

Store in a refrigerator (2° - 8°C). Do not freeze.

Packing:

Single Dose Vial

Mfg / Mkd By:

Natco Pharma Ltd

Doses:


Therapeutic Use:

Cancer

Description:

Introduction
Rasburnat 1.5mg Injection:

Rasburnat 1.5mg Injection is an antihyperuricemic drug belonging to the
category of uricolytic agent, containing the active ingredient Rasburicase. It
is used in the treatment of acute hyperuricemia in patients receiving
chemotherapy. When cancer cells break down, they can release large amounts of
uric acid into the bloodstream. This can cause hyperuricemia, which can lead to
kidney damage and other health problems. Also, this medicine can be used to
prevent or treat hyperuricemia in patients with tumor lysis syndrome(a large
number of cancer cells die within a few periods).

In patients with G6PD deficiency, rasburicase can trigger
hemolysis(destruction of RBC) by generating reactive oxygen species that damage
red blood cells. As a result, rasburicase is generally contraindicated in
patients with G6PD deficiency. If you are diagnosed with this deficiency,
inform your physician before taking this medicine because you will be more
likely to experience severe haemolytic anaemia or methemoglobinemia(an abnormal
form of haemoglobin). Children who are undergoing chemotherapy for leukaemia,
lymphoma, or solid tumor malignancies are at risk for developing hyperuricemia,
which can lead to kidney damage, seizures, and other complications. This drug
helps to treat hyperuricemia by rapidly reducing the levels of uric acid in the
blood. It is important to closely monitor children who are receiving Rasburnat
1.5mg Injection for any signs of allergic reactions, hemolysis (breakdown of
red blood cells), or any other side effects. Talk with your healthcare provider
if you have kidney or liver disease, vision problems and lung problems. Your
healthcare provider will check regular blood tests to prevent complications.
Avoid consuming alcohol as it may cause dizziness.

Consult your doctor before using this medication if you are pregnant or
plan to have a baby. Rasburnat 1.5mg Injection are unsafe to use during
pregnancy as it causes harm to an unborn fetus. Your health care practitioner
will conduct a pregnancy test before you start treatment with Rasburicase
Injection. Discuss with your doctor effective birth control methods and utilise
them for at least two weeks following the last dose.

Uses of Rasburnat 1.5mg Injection:

·
Treatment of High uric acid due to chemotherapy

How
to consume Rasburnat 1.5mg Injection:

The medicine will be administered to you by a
healthcare professional in a hospital setting. Rasburicase is given as an
injection into a vein (intravenous infusion) over a period of 30 minutes, once
a day for up to 5 days. The dose, route of administration, and frequency will
be decided by your doctor based on your disease condition and other factors.

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