Generic Name:

Rituximab

Storage Condition:

Store in a refrigerator (2° - 8°C). Do not freeze.

Packing:

50 ml vial

Mfg / Mkd By:

Zydus

Doses:


Therapeutic Use:

Cancer

Description:

Introduction
Enfiera 500mg injection:

Enfiera 500mg injection contains the active constituent rituximab. It is
used for several different disease conditions in adults. It is used alone or
with other medications to treat non-hodgkin’s lymphoma (cancer affecting white
blood cells called B-lymphocytes) and chronic lymphocytic leukemia (a most
common form of cancer that affects B-cells). It is also indicated to treat
moderate-to-severe rheumatoid arthritis (a type of disease where the immune
system attacks the body cells of its own joints) in combination with methotrexate in adults.
Other uses include granulomatosis with polyangiitis or microscopic polyangiitis
(inflammation of blood vessels that mainly affects the lungs and kidneys) in
adults and children 2 years of age and older. It is also used to treat moderate
to severe pemphigus vulgaris (an autoimmune condition that causes painful
blisters on the skin and lining of the mouth, throat, nose, and genitals.

Enfiera 500mg injection belongs to the class of medications called
anti-CD20 monoclonal antibodies. Do not take this injection if you are allergic
to rituximab or any other ingredients of this medicine, have a weak immune
system, or have any severe active infection. Inform your physician if you have
heart disease, heart failure, or breathing problems before initiating the
treatment. Talk with your doctor if you have ever had a hepatitis B infection
because the infection may reactivate again in a few cases and can be severe
sometimes. Pregnancy and breastfeeding are not recommended when you are taking
this injection.

Common side effects of Enfiera 500mg injection include infection of the
blood, reduced red blood cells, dizziness, swelling in the face and body, itchy
skin, diarrhea, increased sweating, and low or high blood pressure. Use
effective contraceptives during the treatment and 12 months after the last dose
if you can get pregnant. This medicine may cause severe infusion reactions
during or within 24 hours after administration. Inform your physician or
healthcare professional if you face any infusion reactions, such as increased
blood pressure, chest pain, headache, breathing difficulties, vomiting, skin
rashes, or throat swelling.

Uses of Enfiera 500mg injection:

·
Non-hodgkin’s lymphoma

·
Chronic lymphocytic leukemia

·
Rheumatoid Arthritis

·
Granulomatosis with polyangiitis or microscopic
polyangiitis

·
Pemphigus vulgaris

How
to consume Enfiera 500mg injection:

It should only be administered by a trained doctor or nurse. Do not
self-administer the injection. Before giving Enfiera 500mg injection, you will
be given other medications (pre-medication) to reduce the possible side
effects. Your doctor will decide the dose and duration of your treatment based
on the disease severity and other factors. It will be given as an intravenous
infusion, and you will be monitored carefully for any unwanted side
effects.

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