Introduction to DYRONIB 50 TABLET:

DYRONIB 50 TABLET contains Dasatinib which belongs to the group of medicines called Tyrosine Kinase Inhibitors. It is used to manage cancers of blood and bone marrow (such as chronic myeloid leukaemia (CML) and philadelphia chromosome positive (Ph+) acute lymphoblastic leukaemia) in adults, adolescents and in children (aged 1 year or above).

It is primarily used in patients when management with conventional therapies is not suitable or fails to provide adequate response.

Leukaemia is the cancer of white blood cells. It is caused due to abnormal growth and multiplication of blood cells within the bone marrow. It is characterized by severe tiredness, breathlessness, increased bleeding tendency, tiredness, anemia, night sweats, fever, chills, frequent infections and weight loss.

During management with DYRONIB 50 TABLET your doctor will closely monitor your health condition through several blood tests to avoid the risk of unwanted side effects. Avoid eating grapefruit or drinking grapefruit juice while taking DYRONIB 50 TABLET as it may increase the risk of side effects.

Before taking DYRONIB 50 TABLET inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have or at risk of developing hepatitis C infection as a precaution.

Avoid concomitant use of antacids or any stomach medicines along with DYRONIB 50 TABLET. Leave a time gap of at least 2 hours between the medicines. DYRONIB 50 TABLET is not recommended for use in pregnant or breastfeeding women.

Men and women taking DYRONIB 50 TABLET must use a suitable contraceptive method to avoid pregnancy while undergoing therapy with DYRONIB 50 TABLET.

The most common side effects of taking DYRONIB 50 TABLET are increased bleeding tendency, increased infections, feeling tired or weak, nausea, vomiting, hair loss, mouth ulcers, changes in taste, inflammation of the food pipe or stomach, muscle pain or spasm, skin rashes, headache, dizziness and weight loss. Contact your doctor if any of these side effect worsens.

Uses of DYRONIB 50 TABLET:

• Cancers of blood and bone marrow (such as chronic myeloid leukaemia and philadelphia chromosome positive (Ph+) acute lymphoblastic leukaemia)

How to consume DYRONIB 50 TABLET:

Take DYRONIB 50 TABLET as advised by your physician. It can be taken with or without meals. Swallow the medicine with a glass of water. Do not crush or chew the medicine.

Try to take DYRONIB 50 TABLET at the same time each day. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition. Do not stop taking DYRONIB 50 TABLET unless advised by your doctor.