Introduction of AZATEND
INJECTION:

AZATEND INJECTION contains
Azacitidine which belongs to the group of medicines called Anticancer agents.
It is used in adults in the management of all sub-types of myelodysplastic
syndromes (MDS, a group of cancers associated with blood and bone marrow), and
certain types of blood cancer known as chronic myelomonocytic leukaemia (CMML)
and acute myeloid leukaemia (AML).

CMML is a type of blood cancer where the bone marrow releases an
excess amount of monocytes (a type of blood cell) into the blood stream,
whereas in AML, the bone marrow releases an excess amount of immature white
blood cells. Both are characterized by recurrent infections, fever, tiredness,
and increased bleeding or bruising.

AZATEND INJECTION is typically used in adults who cannot undergo
stem cell transplantation. Before receiving AZATEND INJECTION, inform your
doctor if you have any lung, liver, kidney, or heart problems.

AZATEND INJECTION is not recommended for use by pregnant or
breastfeeding women. Both men and women of childbearing potential must use a
suitable contraceptive to avoid pregnancy while undergoing therapy with this
medicine. Men may seek advice on sperm preservation, if necessary, prior to
therapy with this medicine.

The most common side effects of receiving AZATEND INJECTION are
increased bleeding, increased infections, tiredness, nausea, vomiting,
diarrhea, constipation, loss of appetite, stomach pain, weakness, pain and
redness at the site of injection, sore nose and throat, cold sores, headache,
dizziness, trouble sleeping, weight loss, ulcers of the mouth or tongue, and
hair loss. Consult your doctor if any of these side effects trouble you.

Uses of AZATEND
INJECTION:

• all
  sub-types of myelodysplastic syndromes (MDS; a group of cancers associated
  with blood and bone marrow)
• Chronic
  myelomonocytic leukaemia (CMML; blood cancer of monocytes)
• acute
  myeloid leukaemia (AML; blood cancer of the WBC)

How to use AZATEND INJECTION:

Your dose and frequency of administration will be decided by
your physician based on your disease condition and other factors. It will be
given to you by a healthcare professional. Do not self-administer.